IJPR  articles are Indexed in SCOPUSClick Here     Impact Factor for Five Years is 0.13 (2013 - 2018).    

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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

ISSN
0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

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Immunostimulating Complexes (ISCOMs): A Potential Adjuvant for Mucosal Vaccine Delivery

Author: UPLOADED BY-ADMIN, C. C. ANAJWALA, R. M. PATEL
Abstract: There is a need for non living adjuvant vectors that will allow a full range of local and systemic immune responses to orally administered purified antigens. Immunostimulating complexes (ISCOMs) are recently developed for vaccines preparation as adjuvant in an industrial use with increase safety, efficacy and convenience for demanding applications. The immunostimulating complex or ISCOM is one adjuvant with multiple adjuvant properties. ISCOM have the ability to stimulate the cell-mediated immune system as well as to enhance antibody production and have the advantage that only a low dose is needed for adjuvant activity. Because ISCOM-based vaccines have now progressed to phase I and II human trials, This review documents our present understanding of the structure, preparation and functional properties of ISCOMs and will describe some recent development and modifications that have been made to enable ISCOMs to be suitable for human applications.
Keyword: Adjuvant, Immune Response, ISCOMs.
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