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Microspheres-Novel Drug Delivery System- A Review
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UPLOADED BY-ADMIN, KALKOTWAR R.S, BAHALKAR TUSHAR, DWIVEDI ASHISH, BANDE SANGRAM, UGARKAR APOORVA
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| Abstract:
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Microspheres are characteristically free flowing material consisting of proteins or synthetic polymers which are biodegradable in nature and ideally having a particle size less than 200 µm and show the ball-bearing effect. As microsphere are controlled release delivery system it offers many advantages over immediate release delivery like reduced dosing frequency, better therapeutic control, fewer side effects, and, consequently, these dosage forms are well accepted by patients. This article aims to provide a comprehensive review of advantages, methods of preparation, mechanism, different types of polymers used in preparations of microspheres, evaluation technique and various application of biodegradable polymeric microspheres. It mainly includes recent application of the fluorescent microspheres like neuronal retrograde tracers, blood flow measurement in tissues, patents and recent marketed formulations of Microspheres etc.
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Microspheres, Patents, Novel Drug Delivery System, Polymer Carrier, Fluorescent Microspheres
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