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Correlation of Fine Needle Aspiration Cytology and Histopathological Diagnosis in Thyroid Lesions: A Comprehensive Review
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| Author:
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T. VAMSI KRISHNA, RAVI BHASKAR, SUKESH
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| Abstract:
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Thyroid lesions, including benign and malignant nodules, are frequently encountered in clinical practice, necessitating accurate and efficient diagnostic methods. Fine Needle Aspiration Cytology (FNAC) is widely used for the initial evaluation of thyroid nodules, while histopathology remains the gold standard for final diagnosis. This comprehensive review evaluates and compares the diagnostic accuracy, sensitivity, specificity, and clinical outcomes of FNAC and histopathological diagnoses in thyroid lesions based on data from 44studies. Our findings reveal that FNAC demonstrates high diagnostic value, especially for malignant lesions, but faces limitations in certain cases, particularly with follicular lesions and indeterminate cytology. Histopathology remains essential for definitive diagnosis, particularly in cases with inconclusive FNAC results. This review highlights the importance of a combined approach to enhance the diagnostic accuracy and clinical management of thyroid lesions.
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| Keyword:
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Thyroid lesions, Fine Needle Aspiration Cytology (FNAC), Histopathology, thyroid nodules, Malignancy, Indeterminate cytology.
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2025.17.01.003
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| Download:
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