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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Vasculosyncytial Membrane & Syncytial Knots in Preeclampsia

Author: GEETANJALI U. YADGIRE, SHOBHA S. RAWLANI, DEEPALI G. VIDHALE, ANUPAMA SAWAL (CHAUHAN)
Abstract: Background: Reproduction is a feature exhibited by all organisms. In human beings, the mere intrauterine existence of foetus is dependent on one vital organ ‘the Placenta’. Several pathological changes which affect growth of foetus have been described in the placenta in preeclampsia. Out of that syncytial knots & vasculosyncytial membrane (VSM) were the most evident in our study. Objectives: To study syncytiotrophoblasts & vasculosyncytial membrane in terminal villi of placenta. To correlate their changes with placental perfusion. Material and methods: We studied 100 specimens of placenta in each group of normotensive and hypertensive patients. Specimens were collected from labour room and Operation theatre of Gyn. Department of our college. Gross as well as histological changes alongwith foetal outcome were studied for both the groups. Observation & results: There were reduction in weights of placentas and also the fetuses of hypertensive patients. On considering the histological features, syncytial knots were increased and there was paucity of vasculosyncytial membrane in the hypertensive placentas.
Keyword: preeclampsia, pregnancy induced hypertension (PIH ),syncytial knots (SK ) , vasculo- syncytial membrane(VSM ),placental perfusion.
DOI: https://doi.org/10.31838/ijpr/2024.16.03.009
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