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A Comprehensive Review On Challenges In Paediatric Dosage Form
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| Author:
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NEELAM SINGH, PRIYA DIWEDI, POOJA CHAUHAN, DURGESH KUMARI GUPTA, SURYA PRAKASH GUPTA
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| Abstract:
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The development of pediatric dosage forms is particularly difficult due to a variety of factors relating to pediatric population differences from adult populations. The main issues associated with these pediatric dosage
forms development, particularly clinical and physiological factors, are discussed in this review. Both contribute to a well-balanced approach to emphasizing critical safety and efficacy warnings for the of medications within
pediatric populations. Despite the importance of investigating medicines for children, there is still a demand for pediatric-specific formulations and dosage forms accordance with various diseases. Many formulations and dosage forms can be designed, among which the buccal drug delivery seems a good modality for pediatric friendly dosage forms. In addition, formulation developments and regulatory expectations are highlighted. In turn, suggestions are made to potentially improve future pediatric formulation development.
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| Keyword:
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Pediatrics, dose, formulation development, oral, buccal, regulatory, excipients.
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.03.534
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| Download:
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Request For Article
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