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The Role Of Retinol Binding Protein-4 In Type 2 Diabetes
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| Author:
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YASEEN KHASHMAN HUSSEIN, ZAINAB SAMIR YAHYA HAMMO
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| Abstract:
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Background: Retinol binding protein 4 (RBP4), which is a type of adipokine, plays a role in the metabolism of lipids and insulin resistance through a complex network of regulations. It has been recently found that RBP4 is
linked to various risk factors for cardiovascular diseases (CVDs) in patients with type 2 diabetes mellitus (T2DM).
Aims: The purpose of this study is to investigate the relationship between serum RBP4 and certain indicators of glycemic control, dyslipidemia, hypertension, and obesity in Iraqi patients with type 2 diabetes. A total of
sixty (60) patients with type 2 diabetes took part in this cross-sectional study..
Materials and Methods: This study conducted took place from July 2023 to September 2023 at the National Diabetes Center, which is affiliated with Al-Mustansiria University in Baghdad. It was a cross-sectional study involving 60 male patients who have been diagnosed with type 2 diabetes and are between the ages of 30 and 70. Additionally, there were 30 controls included in the study.
Results: The levels of Serum RBP4 are found to be higher in patients with Type 2 Diabetes Mellitus who also have dyslipidemia or obesity. Moreover, there is a positive correlation between Serum RBP4 and certain factors such as body mass index, fasting blood glucose, insulin, HDL, TNF-a, and low density lipoprotein cholesterol. On the other hand, Serum RBP4 shows a negative correlation with Triglyceride and total cholesterol levels.
Conclusion: Serum RBP4, in T2DM Iraqi patients, is correlated with poor glycemic indices, dyslipidemia, and obesity, which are among many risk factors.
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| Keyword:
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Role, Binding, Protein, Type
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2024.16.01.004
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| Download:
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