To evaluate effects of combination of topical 5% Phenylephrine and 0.8% Tropicamide on Pulse Rate and Blood Pressure
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Author:
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SHIKHA OHLYAN, ASHWANI KUMAR GHAI, SURAKSHYA RAJAURE, NIKITA SETHI
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Abstract:
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Background: Dilation of pupil in Ophthalmic OPD is a routine procedure. Whether a sympathomimetic agent like phenylephrine should be used in hypertensive patients is still a question to be answered. This study tries to resolve the issue.
Objective: To evaluate cardiovascular effects of combination of topical 5% phenylephrine and 0.8% Tropicamide.
Method: Total 150 patients were subjected for this study (male and female) between 30-80 years of age. Combination of 5% phenylephrine and 0.8% tropicamide eye drops was instilled at an interval of 15 minutes thrice in the eyes of each patient. Any change in BP or HR was recorded
Result: The data was collected and subjected to appropriate statistical method using R software version 4.2.1. This study has shown no significant increase in Blood Pressure and Heart Rate after instillation of 5% Phenylephrine and 0.8% Tropicamide eye drops except in one case.
Conclusion: We conclude that combination of 5% Phenylephrine and 0.8% Tropicamide can be safely used in all patients who come for ocular examination but precautionary measures should be taken in hypertensive patients.
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Keyword:
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Pulse rate; Blood pressure; Tropicamide; Phenylephrine
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EOI:
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DOI:
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https://doi.org/10.31838/ijpr/2023.15.01.016
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