*Five Years Citation in Google scholar (2016 - 2020) is. 1451*   *    IJPR IS INDEXED IN ELSEVIER EMBASE & EBSCO *       

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
ISSN
0975-2366
Current Issue
Article In Press
No Data found.
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
 

Article Detail

Label
Label
Stability And Invivo Studies Of Mucoadhesive Buccal Tablets (Repaglinide) For Management Of Diabetes

Author: THEJOVATHI B, AKHILESH K SINGHAI
Abstract: Repaglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus. The main objective of the study was to formulate and evaluate bioadhesive buccal tablets to avoid the first pass metabolism in liver. Bioadhesive buccal tablets were prepared by direct compression method using bioadhesive polymers like HPMC K4 M, HPMC K15 M, Chitosan, HPMC K100 M, Sodium CMC, Carbopol 974 P, Sodium Alginate, Gum karaya and Carbopol 941NF in different ratios. In vivo mucoadhesive behavior of optimized formulation was performed in New Zealand rabbits and pharmacokinetic parameters were evaluated. The Stability studies were carried out for best formulation
Keyword: Repaglinide, buccal tablet, Stability studies, In vivo permeation.
DOI: https://doi.org/10.31838/ijpr/2023.15.01.005
Download: Request For Article
 




ONLINE SUBMISSION
USER LOGIN


Username
Password
Login | Register
News & Events
SCImago Journal & Country Rank

Terms and Conditions
Disclaimer
Refund Policy
Instrucations for Subscribers
Privacy Policy

Copyrights Form

0.12
2018CiteScore
 
8th percentile
Powered by  Scopus
Google Scholar

hit counters free