Synthesis, Characterization, Biological Activity DNA cleavage of metal complexes schiff bases containing Imidazolidine Moiety
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Author:
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, ABDUL SALAM ABDUL KAREEM ABDUL RAHMAN, REHAB KADHIM RAHEEM ALSHEMARY
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Abstract:
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New binuclear transition metal complexes 6 bearing the bioactive Imidazolidine analogs were prepared and distinguished by spectroscopic and elemental analysis methods were used to investigate the ligands and their complexes .
Furthermore, as demonstrated by gel electrophoresis, these chemicals induce cleavage in CT-DNA. Furthermore, the complexes were tested for antibacterial activity in vitro and free ligands and solvent control. As a result, the complexes are more active than the free ligands.
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Keyword:
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Biological Activity. Heterocyclic compounds. Pyridazine. DNA Binding
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EOI:
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-
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DOI:
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https://doi.org/10.31838/ijpr/2022.14.04.012
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