The association between depression symptoms and serum vitamin D concentrations in older adults
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Author:
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AMAL MOHAMMAD BADAWOUD
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Abstract:
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Experimental studies have shown that vitamin D metabolites play a role in mood disorders and cognitive function. Because vitamin D deficiency is treatable, studies can be used to influence preventive efforts against vitamin D deficiency. Therefore, this study aimed to assess the relationship between vitamin D levels and depression symptoms in a large, nationally representative sample population of older adults.
The National Health and Nutrition Examination Survey (NHANES) 2013–2014 data were used. Depression symptoms were assessed using the Patients Health Questionnaire-9 (PHQ-9). Chi-square tests were conducted to summarize the study variables by depression status, and multiple logistic regression was performed to assess the relationship between depression symptoms and vitamin D levels (as a total of 25-hydroxyl cholecalciferol and calcidiol).
The findings suggest that low serum vitamin D levels were significantly associated with self-reported depression symptoms (P 0.0001). When adjusted for other predictor variables, this association was not statistically significant. However, the trend suggests that older adults with extremely deficient, deficient, or insufficient vitamin D levels were more likely to have depression symptoms than individuals with sufficient serum vitamin D.
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Keyword:
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Depression, vitamin D, older adults, National Health and Nutrition Examination Survey (NHANES).
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EOI:
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DOI:
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https://doi.org/10.31838/ijpr/2022.14.03.013
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Download:
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Request For Article
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