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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Study of the antioxidant effect of fixed oil, alcoholic extract and phenolic compounds of cumin seeds (Cuminum cyminum)

Author: , DR.HASAN MOHAMMED HASAN
Abstract: In this study, the extraction of fixed oil, preparation of alcoholic extract and separation of phenolic compounds from the seeds of the local cumin plant and their diagnosis by HPLC technique, the diagnosis showed that the seeds of the plant contain phenolic compounds (Chlorogenic acid, Kaempferol, Quercetin, Caffeic acid and Apigenin). The study included comparing the inhibitory effect of the fixed oil, alcoholic extract and phenolic compounds of the free radical DPPH at concentrations of (400) µg/ml and comparing them with the synthetic antioxidant ascorbic acid. (98.03)%. And the least significant results in the inhibition of free radicals are for the fixed oil at a concentration of (100 and 200) µg/ml with percentages of (73.5%, 78.6%), respectively. The results determined that the higher the concentration of the compounds in general, the greater the inhibition of free radicals, because these high concentrations of hydrogen proton contained in high proportions, which caused the stability of free radicals.
Keyword: Cuminum cyminum, Free radicals, DPPH, Fix oil.
DOI: https://doi.org/10.31838/ijpr/2022.14.03.011
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