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Chemistry of Quinazolin-4(3H)-ones and their Anti-inflammatory activity: A Review
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| Author:
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POONAM SINGH, PAYAL RATHI, SHIWANI SINGHAL, CHATRASAL SINGH RAJPUT
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| Abstract:
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Nitrogen containing compounds are very important heterocyclic derivatives in the field of medicinal chemistry. Quinazolinones are very useful heterocyclic compound have a wide range of biological activities like anti-HIV, anti-cancer, anticonvulsant, antifungal, analgesic and anti-inflammatory antibacterial, activities. Promising biological importance of quinazolinones have prompt the scientist to explore the chemistry of quinazolinones as a new anti-inflammatory agent. The exploitation of quinazoline-4-(3H)-one core as a new anti-inflammatory agent has gained momentum recently. The purpose of this current review is to provide an overview chemistry and anti-inflammatory activity of various quinazolin-4(3H)-one derivatives.
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| Keyword:
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Quinazolin-4-(3H)-one, synthesis, anti-inflammatory activity
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2022.14.03.006
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| Download:
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