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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Evaluation of the lethality of fractional extracts of Artemisia vulgaris on the Artemia salina larvae.

Author: , HOANG THANH CHI, BUI THI KIM LY
Abstract: Objective: To test the lethality of Artemisia vulgaris fractional extracts on Artemia salina larvae. Methods: A brine shrimp lethal assay was performed in two timelines of treatment exposure to detect bio-effects in different fractions of the extract. Results: The extracts had a significant impact after 24 hours of exposure, with LC50 values of 183.60 ± 7.40; 164.50 ± 9.10; 264.80 ± 19.20 and 511.30 ± 31.10 183.60 ± 7.40; 164.50 ± 9.10; 264.80 ± 19.20 and 511.30 ± 31.10 (µg/mL) for chloroform, n-hexane, ethyl acetate, and water, respectively. Conclusion: The chloroform and n-hexane extracts had the most effective lethality on larvae viability.
Keyword: Artemisia vulgaris, Artemia, toxicity, brine shrimp lethalty.
DOI: https://doi.org/10.31838/ijpr/2022.14.02.002
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