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In vitro Anti – Inflammatory Activity of Calotropis Gigantea Linn. Leaves Extract
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| Author:
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UPLOADED BY-ADMIN, MOHAMMED RAGEEB MOHAMMED USMAN, S. D. BARHATE
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| Abstract:
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To evaluate the anti-inflammatory activity of the alcoholic extract of Calotropis gigantea Linn. Leaves by in vitro method.
Calotropis gigantea Linn. Leaves were extracted with 90% ethanol and the extract was screened for in vitro antiinflammatory
activity at the doses of 200, 400 and 600 mg/kg using Muzushima and Kabayashi method. Ibuprofen
(100mg/kg) was used as standard reference drug. The % inhibition of denaturation produced by Calotropis gigantea Linn.
Leaves extract at the dose of 200, 400 and 600 mg/kg was 44.5%, 62.2% and 81.8% respectively when compared to control.
The % inhibition of denaturation produced by Calotropis gigantea Linn. leaves extract at the dose of 600 mg/kg was
comparable with that produced by Ibuprofen (85.71%). The present study indicates that Calotropis gigantea Linn. Leaves
extract possess significant anti – inflammatory activity.
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| Keyword:
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Calotropis gigantea linn. Anti-inflammatory, In-Vitro.
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| EOI:
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| DOI:
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