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Method Development And Validation For The Estimation Of Celecoxib In Bulk And Dosage Form By Rp-Hplc.
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| Author:
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MADHAV A.SHETKAR, SIDDHESHWAR.S.PATIL, SHIVAPPA N.NAGOBA, CHANDRAWADAN V.PANCHAL
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| Abstract:
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The goal of this study is to develop and validate an RP HPLC technique for estimating Celecoxib in both bulk and pharmaceutical dose forms. A thorough review of the literature found that there are ways available, but
none of them are as straightforward, specific, exact, or accurate as the established approach for estimating Celecoxib. The chromatographic separation was obtained utilising an isocratic mode of elution on a Thermo Scientific Separation HPLC with a stationary phase of Lichro CART 250-4 (Lichrospher 100) – RP 18e – (5 m) column and a mobile phase of Methanol: Water. A UV detector set to 236.0nm was used for detection.According to ICH criteria, the devised approach was validated.
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| Keyword:
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RP-HPLC, Method development, Validation, Celecoxib
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.03.525
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| Download:
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Request For Article
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