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Neurosurgical Treatment-Drug - Drug Interactions
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| Author:
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GILLELLA PRANEETH, SRIDHAR BABU GUMMADI
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| Abstract:
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The present study was a cross-sectional retrospective study, carried out by using automated medication records of 285 randomly selected patients who had been admitted to neurology ward and receiving at least two medications. Initially, demographic information of patients such as age, gender, and clinical diagnosis were recorded and incomplete patients’ records were excluded from the study. The entries of all prescribed drugs to the selected patients from the date of admission till the date of discharge were made. Patients with major severity were screened out. Categorization of clinically potential DDIs was made on basis of Onset, severity and scientific evidence. Among 280 patients of neurosurgical ward 201 patients had the drug-drug interactions and remaining 79 patients were not found any drug-drug interactions. In total of 638 drug-drug interactions some documented and which are categorized as excellent 84, good 180, fair 310 and some are not documented 64 drug interactions. Based on the severity of drug-drug interactions the potential drug-drug interactions categorized as contraindicated in 27 (04.32%) patients, major severity in 399 (62.50%) patients, moderate severe in 199(31.01%) and minor severity in 14(02.01%) patients.
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| Keyword:
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Neurosurgical disorder, drug-drug interaction, thiopentone and suxamethonium
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.04.686
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| Download:
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Request For Article
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