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Accelerated Stability Test Of Snakehead Fish (Channa striata) Extract and Kelulut Honey (Heterotrigona itama) Ointment Combination With Alpha Tocopherol As An Antioxidant
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| Author:
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, MOHAMAD ANDRIE, WINTARI TAURINA, NATA HADIATI ARIFANI
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| Abstract:
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Snakehead fish extract and kelulut honey can speed up the wound healing process so they are formulated into ointments based on adeps lanae. Adeps lanae can be degraded due to the oxidation process so that it can cause the formation of volatile compounds that cause rancidity. The addition of alpha-tocopherol as an antioxidant in the ointment can prevent the rancidity of the base of adeps lanae. The objective of this study is to determine the effect of the addition of alpha-tocopherol as an antioxidant in the preparation of snakehead fish extract ointment (Channa striata) and kelulut honey (Heterotrigona itama) on the physical properties and acid number tests. for a storage time of 28 days at a temperature of 40 ± 2oC and RH 75 ± 5%. Variations of alpha-tocopherol used were 0.001%, 0.01%, and 0.05% then tested for physical properties and an acid number of the preparation. The dispersion test showed that the preparation did not meet the 5-7 cm requirement. The results of the analysis on the dispersion showed a significant difference between F0, F1, F2, and F3 so that it can be concluded that the preparation was unstable. The results of the adhesion analysis showed that there was no significant difference in each formula. The results of the stability test showed that all formulas had good physical stability, providing protection. The preparation also experienced a decrease in oxidation at F3 compared to F0 and F2 which was indicated by a decrease in acid number.
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| Keyword:
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Snakehead Fish, Honey Kelulut, Adeps Lanae, Alpha-Tocopherol, Accelerated Stability
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.03.226
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| Download:
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