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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Drug Utilization Evaluation of Antibiotics Used in Orthopaedics Department in A Tertiary Care Hospital of Pathanamthitta District, Kerala

Author: , PHILIP JACOB, ARUL BALASUBRAMANIAN, KOTHAI RAMALINGAM
Abstract: Drug Use Evaluation (DUE) or Drug Utilization Evaluation is the management of continuous, precise, criteriabased assessments of the use of drugs, which will warrant that the drugs are being used relevantly, which is at the discretion of the patient. The study aims to determine the drug utilization evaluation of Antibiotics used in the Orthopaedics department at a tertiary care hospital; to assess the culture sensitivity with various antibiotics and identify the most effective antimicrobial against the organism isolated. A prospective observational study was used for the assessment. A sample size of 60 patients who had undergone the antibiotics treatment was selected for this study. The descriptive of the sample study shows 78.3% of the patients were male and 21.7% were female. Age-wise distribution found that 46.7% of the patients were predominant, within the age group of 20-40 years, followed by 26.7% in the age group of 41-60 years. The most common reason for the admission to the orthopaedics department was fracture with a percentage of 65% due to motor accidents especially bike accidents. Analyzing the use of antibiotics on the study sample reveals that 33.4% of the patients received only Cephalosporins, followed by aminoglycosides 31.6 % and less by other antibiotics. The most predominant cephalosporin prescribed in this study was Cefazolin (46.3%). The most widely used aminoglycoside antibiotic was Vancomycin. In the study of isolation of organisms, the majority of the samples undergone culture and sensitivity tests. In this, it was found that 91.2% were Gram – ve and 08.8% Gram + ve organisms. Drug utilization review of antibiotics is an important tool for health care professionals to identify the effective use of antibiotics.
Keyword: Drug Utilization Evaluation; Antibiotics; Orthopaedics; Culture sensitivity Test.
DOI: https://doi.org/10.31838/ijpr/2020.12.04.671
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