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Osteoporosis Risk In Postmenopausal Women With Type Ii Diabetic Mellitus, Samut Songkhram, Thailand
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| Author:
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YUTTANA SUDJAROEN, PIMPORN THONGMUANG
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| Abstract:
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Type 2 diabetes mellitus (T2DM) is implicating with lower bone mineral density (BMD), calcium imbalance, vitamin D disturbance and microvascular disease. This study was determined BMD level in postmenopausal women and dividing to normal BMD and low BMD (including osteopenia and osteoporosis) groups; to compare diabetic parameters including HbA1c and serum Cr between two groups; and to correlate BMD, HbA1c and serum Cr in postmenopausal women. BMD was measured by calcaneal ultrasound bone densitometer. HbA1c was measured from EDTA tube by automatic analyzer. Serum Cr from clotting blood tube was extracted and analyzed by Inductively Coupled Plasma-Optical Emission Spectrometry (ICP-OES). Seventy of postmenopausal women were recruited in this study and there were divided to normal and low BMD groups (n = 24 and 46, respectively). Age of normal BMD group was lower than low BMD group. Average of HbA1c from low BMD group was out of reference range and significantly different to normal BMD group (p = 0.006). In addition, serum Cr of normal BMD group was higher significant (p = 0.032). Low BMD postmenopausal women were risk to T2DM due to high level of HbA1c with lower serum Cr. BMD was negative related to HbA1c and serum Cr. Serum Cr was related to BMD, which may additional biochemical marker to useful in risk of T2DM and osteoporosis.
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| Keyword:
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bone mineral density, osteoporosis, postmenopausal women, serum chromium, Type 2 diabetes mellitus (T2DM)
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.01.801
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| Download:
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Request For Article
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