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Isolation and characterization of secondary metabolites from endophytic fungi, Aspergillus tubingensis strain CS/7/2 from leaves of Andrographis paniculata (Burm. f.) Nees
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| Author:
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SMITA KISHOR PURI, PRASANNA VASANTRAO HABBU, PREETI VENKATRAO KULKARNI, VENKATRAO HANMANTHRAO KULKARNI
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| Abstract:
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Endophytes are the microorganisms present in the interior tissues of plants and show a mutualistic, symbiotic and trophobiotic relationship. Endophytes are considered to be a good alternative source for production of bioactive secondary metabolites. In the present study, an attempt was made to isolate secondary metabolites from the previously reported endophytic fungi Aspergillus tubingensis strain Cs/7/2 isolated from leaves of Andrographis paniculata. Two known bioactive compounds, andrographolide (1) and quercetin (2) were isolated from n butanol fraction of Aspergillus tubingensis strain Cs/7/2. A spectroscopic analysis, such as FT-IR, mass spectra (MS) and Nuclear Magnetic Resonance (NMR) were compared with reported data to elucidate the chemical structures of isolated compounds. This is the first report on isolation of these compounds from endophytic fungus of Andrographis paniculata. Thus, it can be concluded that, Aspergillus tubingensis strain Cs/7/2 can be favorable start for the production these constituents.
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| Keyword:
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Andrographis paniculata; Andrographolide, Aspergillus tubingensis, Quercetin
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.02.381
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| Download:
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