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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Evaluate the Osteoporosis/Osteopenia in Kidney Transplant Patients After 2 Years

Author: KARIM MOWLA, ELHAM RAJAEI, ALI GHORBANI, ALIREZA SEDAGHAT, ALIREZA GHANBARAN
Abstract: Aim: Bone and mineral disturbances happen commonly in kidney transplant recipients and are affiliated with a high risk of fracture. This study investigates the currency of osteoporosis in transplant patients 2 years after the operation and evaluates possible and related risk factors. Method: The study was performed as a census on all patients who underwent kidney transplantation two years ago. 75 eligible people attended to participate in the research project were divided into three groups based on densitometry results: normal, osteopenia and osteoporosis. Other variables included body mass index (BMI), gender, age, dietary supplementation of calcium, and vitamin D. Quantitative variables of blood pressure, and serum calcium level were also compared in different groups. The relationship between qualitative variables was examined using the Chi-square test, and the mean of each quantitative variable was examined using the Mann-Whitney nonparametric test. Results: Findings revealed that out of 75 eligible people, 30.7% belonged to the age group over 50 years, 69.3% belonged to the age group under 50 years, 57.3% are women, and 42.7% are men. In the present study, based on bone densitometry, participants were divided into normal, osteopenia and osteoporosis. The patient's' body mass index was measured, and there is the highest frequency at the level of BMI 20-25. Conclusion: Current retrospective research has demonstrated that the bone mineral density value, is positively correlated with the female gender and negatively correlated with the Age, Calcium level and BMI and had no significant relation with patients' blood pressure levels.
Keyword: Kidney transplant, Osteoporosis, Osteopenia, Bone densitometer
DOI: https://doi.org/10.31838/ijpr/2021.13.01.786
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