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Evaluation of Relationship between Child-pugh and MELD Scores as Predictors of Disease Severity and Mortality in Cirrhotic Patients and Degree of Esophageal Varices
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| Author:
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SEYED JAVAD HOSEINI MOTTAEZ, MITRA AHADI
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| Abstract:
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Aim: The aim of the present study was to evaluate the relationship between Child-pugh and MELD scores as predictors of disease severity and mortality in cirrhotic patients and degree of esophageal varices.
Materials and Methods: The present study is a cross-sectional study conducted on 63 cirrhotic patients, referred to emergency department or special clinic of Ghaem and Imam Reza hospitals in Mashhad in 2017-2018. After collecting the data, they entered into SPSS software and described using appropriate tables and graphs. In analytical analysis, One Way ANOVA test was used to compare the mean scores in the three groups. Significance level in all tests is less than 0.05.
Results: The results of the study showed that the mean scores of Child-pugh (P = 0.3), Alb
(P = 0.3), cr (P = 0.4), bil T (P = 0.2), bil D (P = 0.2), MELD (P = 0.06), WBC (P = 0.1), HB (P = 0.5), HTC (P = 0.3), PLT (P = 0.3), INR (P = 0.07), AST (P = 0.07) and ALT (P = 0.08) of the studied patients in terms of degree of esophageal varices were not significantly different among the participants. However, the mean ALP score (P = 0.03) of patients in terms of degree of esophageal varices was significantly different among the participants in the study, so that with increasing degrees of esophageal varices, the mean ALP score of patients decreased. The results of correlation test also showed that there was no significant relationship between MELD and Child-pugh score and the degree of esophageal varices.
Conclusion: Based on the results, there is no relationship between MELD and Child-pugh scores and degree of esophageal varices in cirrhotic patients. Thus, a correlation between esophageal varices bleeding and the mortality caused by it and MELD does not necessarily indicate and confirm its correlation with degree of esophageal varices.
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| Keyword:
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Liver cirrhosis, esophageal varices, MELD and Child-pugh
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.01.765
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| Download:
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