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Formulation and Characterization of Chitosan coated Liposome for Sustained Release of bio-actives
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| Author:
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RAJESH SHARMA, MAHENDRA CHOUHAN, KAMLESH DASHORA
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| Abstract:
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The aim of current study was to assess the potential Chitosan coated liposomes formulation. Modified ethanol injection method was adopted and inspects the vesicle morphology. Average particle size was found to be 303.6 nm & entrapment efficiency 78?5 %. In vitro release pattern followed 63.5?0.18 in 24hrs. Prepared formulations have received considerable attention in pharmaceutical and biomedical application, specifically achieving sustained release controlled formulation. Thus, it is a useful method for prolonging drug release from dosage forms, reducing adverse effects and to deliver drugs in a controlled manner.
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| Keyword:
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Liposomes, Chitosan, Release rate, stability, sustain release
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.03.025
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| Download:
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Request For Article
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