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Efficacy and Safety of An Herbal Product in Reducing Symptoms of Knee Osteoarthritis
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| Author:
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SANJIB KUMAR PANDA, LOPAMUDRA ADHIKARI, SAILAJA SAHU
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| Abstract:
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Objectives: Osteoarthritis (OA) is a common, chronic, progressive, skeletal, and degenerative disorder that commonly affects the knee joint which causes the disability of elderly people. This study aimed to assess the efficacy and safety of test supplement in subjects with OA of knee as compared to placebo.
Methods: A total of 50 subjects aged between 40 to 75 years who were suffering from unilateral or bilateral OA of the knee for greater than 3 months (ACR criteria) were enrolled in the study and 47 subjects continued till end. The subjects were enrolled to either the test group or placebo group. The primary endpoint included the Western Ontario and McMaster Universities (WOMAC) Osteoarthritis Index and secondary endpoint included Visual Analog Scale (VAS) scores and WOMAC sub score for the subjects.
Results: After 60 days of treatment, there was a significant reduction in the mean WOMAC and VAS score in test group compared to placebo. It was also found to be safe and well tolerated.
Conclusion: This study results provide a promising result for the test product as a useful alternative treatment option for the management of symptoms of OA.
The registration number: CTRI/2017/06/008874
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| Keyword:
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Osteoarthritis, VAS, WOMAC
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.02.086
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| Download:
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Request For Article
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