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Analytical Method Development and Validation of Rilpivirine by RP-HPLC Method
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| Author:
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, JYOTI A PATIL, ROHIT R SHAH
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| Abstract:
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A new a rapid, accurate and precise method was developed and validated for the estimation of Rilpivirine in pharmaceutical dosage form by reverse phase high performance liquid chromatographic. The Separation was achieved by Agilent Zorbax Bonus-RP (250 x 4.6 mm, 5 µ) column and using Buffer : ACN (20:80) as mobile phase. The flow rate was 1 mL/min and the detection wavelength was 304 nm. The limit of detection (LOD) for Rilpivirine was found be 2.35 µg/ml and the limit of quantification (LOQ) for Rilpivirine was found be 7.13 µg/ml.
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| Keyword:
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Rilpivirine, RP-HPLC, Agilent Zorbax Bonus-RP column, LOD and LOQ.
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.03.066
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| Download:
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Request For Article
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