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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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In vitro Antioxidant and Preliminary Phytochemical Studies of Caralluma fimbriata Wall.

Author: UPLOADED BY-ADMIN, PRIYA D, RAJARAM K, SURESH KUMAR P
Abstract: Preliminary phytochemical analysis and in-vitro antioxidant activity of aqueous, ethyl acetate, ethanolic & methanolic extracts of Caralluma fimbriata Wall. were investigated. The antioxidant activity was studied in some in-vitro antioxidant models like DPPH radical scavenging activity, superoxide radical scavenging activity, ferric reducing power. Total antioxidant capacity was also determined by phosphomolybdate method. Among the phytochemical screening of these extracts, methanolic extract showed that the whole plant was rich in alkaloids, flavonoids, glycosides, phenolic compounds, saponins and quinones.The methanolic extract of Caralluma fimbriata Wall. showed antioxidant activity by inhibiting DPPH, scavenging superoxide and hydrogen peroxide. It also showed reducing power ability in ferric reducing model. Significant antioxidant activity of methanolic extract of Caralluma fimbriata Wall. was found which might be due to the presence of Phenolic compounds. Flavonoids, Phenols, Saponins, glycosides found in the preliminary phytochemical screening. The total phenols and flavonoid contents of aqueous, ethyl acetate, ethanolic & methanolic extracts Caralluma fimbriata Wall. were also measured.
Keyword: Antioxidant, Caralluma, DPPH, Apocynaceae, Phytochemical.
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