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In vitro Antioxidant and Preliminary Phytochemical Studies of Caralluma fimbriata Wall.
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| Author:
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UPLOADED BY-ADMIN, PRIYA D, RAJARAM K, SURESH KUMAR P
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| Abstract:
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Preliminary phytochemical analysis and in-vitro antioxidant activity of aqueous, ethyl acetate, ethanolic & methanolic
extracts of Caralluma fimbriata Wall. were investigated. The antioxidant activity was studied in some in-vitro antioxidant
models like DPPH radical scavenging activity, superoxide radical scavenging activity, ferric reducing power. Total
antioxidant capacity was also determined by phosphomolybdate method. Among the phytochemical screening of these
extracts, methanolic extract showed that the whole plant was rich in alkaloids, flavonoids, glycosides, phenolic compounds,
saponins and quinones.The methanolic extract of Caralluma fimbriata Wall. showed antioxidant activity by inhibiting
DPPH, scavenging superoxide and hydrogen peroxide. It also showed reducing power ability in ferric reducing model.
Significant antioxidant activity of methanolic extract of Caralluma fimbriata Wall. was found which might be due to the
presence of Phenolic compounds. Flavonoids, Phenols, Saponins, glycosides found in the preliminary phytochemical
screening. The total phenols and flavonoid contents of aqueous, ethyl acetate, ethanolic & methanolic extracts Caralluma
fimbriata Wall. were also measured.
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| Keyword:
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Antioxidant, Caralluma, DPPH, Apocynaceae, Phytochemical.
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| DOI:
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