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Sirtuin as Molecular Regulator, Gerontology Tool: A Review of Sirtuin System, Characterization and Function in Molecular Biology
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| Author:
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, REVATHI N, ARJUNANA, NIVETHA C, GOWRI A, SIVA VIJAYAKUMAR T, MUTHUSELVAM M
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| Abstract:
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The single gene that correlates with many genetic diseases and disorders, as well as ageing and age-related
diseases, is the subject of this research. SIRT1 is a gene that plays a role in the ageing process and age-related
disorders including early ageing, vision, Alzheimer's disease, dementia, cancer, skin problems, and so on. The
extraordinary and significant capacity of the quality is to upgrade the telomerase action. Telomerase is the
protein that shields the finish of the chromosomes from the harm. Telomerase goes about as defensive container
layer that forestalls the chromosomes. The shortening of telomerase prompts the way toward maturing. Many
exploration shows that the polyphenolic compound particularly resveratrol from grapes shows dynamic outcome
in the incitement of sirtuins quality and studies shows that the cycle lead expansion of life expectancy. The
examination on the specific quality shws that it includes in different exercises like cell cycle, apoptosis, disease,
Neurodegenerative problems and so forth, The point of the investigation centering towards the significant
exploration work on the sirtuins quality and its capacities in different measurements
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| Keyword:
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Sirtuins, SIRT1, Anti aging, Resveratrol, deacetylase, Mammalian sirtuins, autophagy
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.03.067
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| Download:
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Request For Article
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