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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Histopathological spectrum of benign and malignant lesions of oral cavity in a patient attending Coastal tertiary care hospital – A Retrospective study

Author: , PRASANTHI CHERUKURI, VASUNDARA GARDAS , PENTAKOTA KIRANMAYI
Abstract: Background: In a most densely populated country like India, a quater of the population are tobacco users in some way or the other. In Andhra Pradesh most people have the habit of smoking chutta in which the lighted end is put in mouth and is associated with higher incidence of squamous cell carcinoma of hard palate. Aim: The present retrospective study was undertaken to study the pattern of oral cavity lesions in patients attending a coastal tertiary hospital. Materials and Methods: A two-year retrospective study was performed in the Department of Pathology at GITAM Institute of Medical Sciences and Research, a Tertiary care Teaching hospital located along the coastal belt of Visakhapatnam from Dec 2018 to Dec 2020. A total of 101 patients with oral cavity lesions approached the hospital for whom after taking a detailed history, the lesions were excised and sent for histopathological examination. Results: A total of 101 cases were included in the present study. The age ranged from 6 to 90 years with a mean age group 44.38 years. Out of total 101 cases, 59 (58.41%) were males and 42(41.59%) were females. Male preponderance was seen in malignant lesions with a male to female ratio of 1.8:1. The most prominent site of malignant lesions was the tongue 33 (32.67%), hard palate 19 (18.81%) and cricoid 5(4.95%). The tongue, lip, vocal card and hard palate were the most common sites for both benign and non-neoplastic lesions. Out of 101 oral lesions, 17 (16.8%) of benign type, 35 (34.6%) malignant type and the rest were 49 (48.6%) were non-neoplastic lesions. Conclusion: Benign lesions were most predominant lesions in the oral cavity and squamous cell carcinoma is the most common malignant lesion. Since oral cavity is the most accessible site for clinical examination, early detection and diagnosis will avoid mutilating surgical treatment.
Keyword: Squamous cell carcinoma, histopathological diagnosis, Oral cavity, non-neoplastic lesions, tongue
DOI: https://doi.org/10.31838/ijpr/2021.13.02.479
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