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Therapeutic Potential of Ferric maltol in the Treatment of Iron deficiency anemia: An Evidence-Based Review
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| Author:
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, ARIN NATANIA S, RAJA VIDHYA D, KIRAN KUMAR RATHINAM, SARVESH SABARATHINAM
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| Abstract:
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Background: The oral formulation of ferrous iron have been extensively used in the management of Iron Deficiency Anaemia. However, oral ferrous products have poor absorption and greater side effects. In addition, existing IV Iron therapy is expensive, invasive and intolerable in many patients with IDA. Oral ferric maltol serves as a novel therapeutic agent which is designated for IDA. The main aim of this review is to express the therapeutic use of Ferric Maltol in IDA as well as multiple co-morbidities like inflammatory bowel disorder.
Objectives: To review therapeutic Potential of Ferric maltol in the treatment of Iron deficiency anemia.
Methods: A systematic search of literature was performed via Pubmed/Medline, Embase and Cochrane library using key terms such as 'Ferric Maltol, Ferrous, Iron deficiency anemia, Inflammatory Bowel Disease, Pulmonary Hypertension, Heart failure, Chronic Kidney Disease and Anaemia. Studies were included in this review based on the predefined inclusion criteria.
Result: Ferric Maltol formulation shows a better alteration for iron. Trials showed substantial changes in the Hb and anaemia and Ferritin concentrations in anaemia patients with multiple co-morbidities like IBD, CKD & PH. Emerging finding indicates for IDA & IBD condition. Ferric maltol appeared to increase the serum levels of iron in terms of normalization or an apparent elevation in terms of the levels of Hb and ferritin.
Conclusion: Ferric Maltol is a fairly safe, reliable, cost-effective tolerable oral iron therapy for IDA. Ongoing clinical trials and researches will help to determine the long-term safety and efficacy of Ferric Maltol for enhanced use in future.
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| Keyword:
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Ferric maltol, iron deficiency anemia, inflammatory bowel disease, chronic kidney disease.
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.02.444
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| Download:
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