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Formulation and Evaluation of Ferulic Acid-Lipid Phytosomal Gel for its Antioxidant Activity (The Ferulic acid lipid Phytosomal gel was formulated and evaluated with different parameters and then assessed for its antioxidant activity)
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| Author:
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SONU RANI, SHILPA PAHWA, PREETI MAAN
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| Abstract:
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Background and objective: Nowadays, Herbal products attract the world’s whole population because of their safety features. For the efficient delivery of herbal compounds in various health conditions, many technologies have been tried, denominated NDDS. Ferulic acid has many biological activities, but due to low bioavailability caused by high elimination rates, conventional drug delivery carriers fail to reach their objectives. Phytosomal gel of ferulic acid may be proven as the best drug carrier to enhance bioavailability and lower the elimination rate. This study aimed to formulate Ferulic acid-lipid phytosome gel to enhance stability and bioavailability.
Material and method: Phytosomal complex of ferulic acid was prepared using solvent displacement methods, and the ferulic acid-lipid phytosome gel was prepared using carbazole as a gelling agent. The complex was characterized by UV, SEM, and FTIR analysis. The gel was evaluated for its pH, viscosity, spreadability, SEM, and FTIR.
Result: The result highlighted the potential use of ferulic acid and the benefits of phytosomes as a drug carrier.
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| Keyword:
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Phytosome; Ferulic Acid; Novel drug delivery system; Herbal compound
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.02.426
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| Download:
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