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Alpha Arbutin as a Skin Lightening Agent: A Review
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| Author:
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NIKHIL CHANDORKAR, SRUSHTI TAMBE, PURNIMA AMIN, CHANDU S MADANKAR
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| Abstract:
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For decades, possessing a lighter skin color has been known as a characteristic of elegance and superiority. The use of skin lightening agents is still prevalent across the globe despite strict regulations and public health campaigns against them. This can be attributed to the misleading marketing of harmful skin bleaching agents under the name of skin brighteners, skin toners, or dark spot removal creams that are readily available. In an effort to find a safer alternative to hydroquinone and other harmful skin lighteners, extensive research culminated in the discovery of a-arbutin. It acts by inhibiting tyrosinase activity and melanosome maturation. It is one of the most popular skin lightening ingredients in the world at present and has been used in the treatment of many hyperpigmentation disorders. a-arbutin has a high market value due to its wide applicability in the cosmetics and pharmaceutical industries. In this review, we have discussed the physiochemical properties of a-arbutin and safety profile, its mechanism of action, recent advances in the delivery of a-arbutin for skin lightening, various combination treatments, and current market status. This literature review presents a futuristic scope of a-arbutin as a safer alternative to other harmful skin lightening agents.
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| Keyword:
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Alpha arbutin, skin lightening, cosmetic, hyperpigmentation, melanogenesis
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.02.446
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| Download:
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