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Vitamin D, hormonal and metabolic disturbances in polycystic ovary syndrome
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| Author:
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SHALAN H B AL-SAEDY, MAHDI MTHUWAINI, ALI E AL-SNAFI
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| Abstract:
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Polycystic ovarian syndrome (PCOS) is multifactorial endocrine disorder affecting women in child bearing age and is considered as one of the main cause of infertility.This study was design to correlate between the disturbance of LH, FSH, testosterone, estradiol, progesterone and metabolic parameters with AMH, and vitamin D in polycystic ovarian syndrome in woman. Fasting blood samples were collected from 60 patients (20-40years) with PCO attending Al-Shatra hospital, Bint AL-Hoda and Al-Hussein teaching hospital in Thi-Qar governorate- Iraq, who diagnosed by gynecologists, In addition to 30 healthy control, through the period from 1 sepetember 2020 until the end of November 2020. PCOS showed significant elevation of serum level of LH (P< 0.01), FSH (P< 0.05), LH/FSH ratio (P< 0.05), testosterone(P< 0.01), progesterone (P< 0.05), antimullerian (P< 0.001), glucose (P< 0.01), total cholesterol (P< 0.01), triglycerides (P< 0.001), LDL (P< 0.01), VLDL (P< 0.05) and Vitamin D (P< 0.01), while there were significant decline in the serum level of estradiol (P< 0.01), and HDL (P< 0.01). The impact of vitamin D in the ovary might potentially encourage the use of vitamin D as an adjunct therapy in treatment of PCOS.
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| Keyword:
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PCOS, Vitamin D, AMH, hormonal disorders, metabolic disorders
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.02.406
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| Download:
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