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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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A Biological Comparative Study of a-Terpineol in Normal and Nanoparticle Size

Author: , MOHAMED M ABOU-ELZAHAB, EMAN M ELGENDY
Abstract: a-Terpineol was compared at normal and nanoparticle size. It has been subjected to extensive research. Employing hemolysis of erythrocyte and ABTS methods, a-terpineol has been tested as a natural antioxidant. The highest inhibitor of nano a- terpineol was shown in hemolysis and medium inhibitor in ABTS method. Moreover, a-terpineol was examined for the cytotoxic activity. Nano a- terpineol has shown good inhibition rate on the cell lines of hepatocellular and colorectal carcinoma. On the other hand, a-Terpineol at normal size showed less activity towards all tests. This research declares that a-terpineol has perfect antioxidant agent and this effectiveness increases when it becomes at nanoscale size and its efficacy as anti-cancer has increased.
Keyword: a-Terpineol, Nano particle, erythrocyte hemolysis, ABTS, cytotoxic, carcinoma
DOI: https://doi.org/10.31838/ijpr/2021.13.02.359
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