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Mechanism Ethnomedicinal and Phytochemical Effect of Ayurvedic Plants in Prevention and Management of Senile Dementia of Alzheimer’s Disease: A Review
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| Author:
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RINKI KUMARI, ANJALI VERMA, DISHA SHARMA, SUDHANSHU MISHRA, AJAY KUMAR SAHI, SHRAVANYA GUNDU, NANKI SINGH, JASMEET SINGH, SIMON AGONGO AZURE, ANITA VENAIK
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| Abstract:
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In the current scenario, there are negligible or no approved anti-neurodegenerative therapies globally; only the
conventional drugs provide very short-term relief. For centuries, due to multi-component and multi-target
approaches of herbal or natural medicines have been used to treat various neurodegenerative like senile
dementia and Alzheimer’s disease. The present review reveals several most prominent medicinal plants and
their respective constituents, utilized in traditional medicine systems for cognitive impairment treatment, and
various biomarkers have been discussed. This review attempts to direct the urgent need for new and proved
herbal therapeutic agents to obviate neurogenesis.Most of predominant neuro-degenerative such as
Alzheimer’s disease has ailment characterized by progressive cognitive deterioration. This highlights the urgent
need for new and improved herbal-based therapeutic agents to obviate neurogenesis.Various biomarkers have
been well established which diagnose neurodegenerative diseases such as SD (Full Form) and AD, which is
linked with an assortment of symptoms, nowadays almost 100 impending new herbal medicines are currently
developed. The present review is expected to provide an into the current progress of herbal antineurodegenerative drugs, with a particular focus on their mechanism to escort target. We expect this review
to provide a rational perspective-management vision on the significance of future anti-neurodegenerative herbal preparations to be effective in the preclusion and managing various neurodegenerative.
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| Keyword:
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Alzheimer’s disease, senile dementia, amyloid peptide, anti-oxidant activity, anti-inflammatory, and memory loss.
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.02.333
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| Download:
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