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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Chronic Hepatitis B and Waram al-Kabid Muzmin: Historical Perspective

Author: AYSHAH HASHIMI, M AKHTAR SIDDIQUI, YASMEEN AHMAD, MANTASHA BINTH SIRAJ
Abstract: Complementary and alternative medicine is a rich source of information for various diseases as well as their management. But there is wide gap between the ancient and contemporary concept in pathophysiology of the diseases. Chronic Hepatitis B is a necro-inflammatory disease of liver caused by persistent infection with Hepatitis B Virus for more than 6 months. Many studies suggest that folks have been existing with the virus for thousands of years as scientists find evidence of HBV in human genomes from Eurasian remains dating from around 200 to 4,500 years ago. After carrying out historical review of the literature available on the subject, it is observed although Hepatitis B as a disease per se is not mentioned as a separate entity and understandably so, as Hepatitis due to hepatitis B virus infection has been very recently established. But classical literature is replete with detailed information of liver (Jigar) diseases and Waram al-Kabid is vividly described by ancient Unani scholars. Zakariya al-Razi (Rhazes), has mentioned in his book Al-Hawi fi al-Tibb (Continens Liber), about the epidemic jaundice, first described around 400 B.C. by Hippocrates (Buqrat). It is also observed that the classical Unani literature is resplendent with hepatoprotective drugs (Muqawwi -i-Jigar). With the help of this review of classical literature along with modern concept an effort is made to put them in correct perspective.
Keyword: Waram al-Kabid, Chronic Hepatitis B, cirrhosis, hepatoprotective activity, Muqawwi -i-Jigar
DOI: https://doi.org/10.31838/ijpr/2021.13.02.295
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