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Quantitative Analysis And Analytical Method Validation For Api &Formulated Dosages Of Voglibose By Uv Spectroscopy
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| Author:
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PREETI NAND KUMAR, R.N.SHUKLA
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| Abstract:
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An alpha-glucosidase inhibitor Voglibose is used for lowering blood glucose levels in people with diabetes A very straight forward, quick, responsive and accurate UV- Spectrophotometric method of analysis have been developed for assessment of Voglibose in pharmaceutical formulation. Since Voglibose only absorbs UV in the low wavelength area, it cannot be identify with high sensitivity. Voglibose has shown successful results for various analytical instruments only in the permutation of Taurine and Sodium periodate. The API was derivatives using Taurine and Sodium periodate in water and methanol. Drug exhibited distinct ?max in methanol at 281nm. Linearity was observed in the concentration range 10-80 µg/ml. The method was validated by recovery studies. The methods used are inexpensive and sensitive for the inference of Voglibose in bulk drug and tablet dosage forms.
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| Keyword:
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Anti diabetic agent, UV- Spectrophotometry, Voglibose, Glucosidase, Quantitative analysis,
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.02.238
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| Download:
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