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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Anti-Tubercular Treatment Induced Stevens Johnson Syndrome (Ten Overlap) - A Case Report

Author: MS PRIYANKA SUHAGIYA, DR.AKHILESH KUMAR MAURYA
Abstract: Stevens-Johnson syndrome (SJS) is a rare, serious disorder of the skin and mucous membranes, also known as erythema multiform majus, it is a potentially fatal condition that manifests widely on the skin and mucosal surfaces, but also other vital organ. In 95% of case reports, drugs were found to be an important cause for the development of SJS. We report a case of a 46-year-old female known case of Pulmonary Tuberculosis was on treatment – Anti tubercular drugs. Fifteen days after commencement of anti TB treatment she developed diffuse erythematous rashes over face, trunk and both extremities. There were ulcers on oral cavity. A diagnosis of Drug induced Stevens Johnson’s syndrome (SJS) /TEN overlap (skin detachment levels of 10% - 29% of the body surface area covered with erythema) was made.
Keyword: Anti Tubercular Treatment, Stevens Johnson syndrome, Toxic epidermal necrosis, erythematous rash.
DOI: https://doi.org/10.31838/ijpr/2021.13.02.242
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