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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Medicinal Significance of Coumarins: A Review

Author: UPLOADED BY-ADMIN, SHRIRAM H. BAIRAGI, POOJA P. SALASKAR, SONAL D. LOKE, NILAM N. SURVE, DARSHANA V. TANDEL, MITESH D. DUSARA
Abstract: Coumarin is a chemical compound found in many plants. It is a bitter in taste, appetite suppressant, and is probably produced by plants as a defense chemical to discourage predation. The most useful method for the synthesis of Coumarin is from phenol and ethyl acetate and also by using catalyst. Coumarin is used in the pharmaceutical industry as a precursor molecule in the synthesis of a number of synthetic anticoagulant pharmaceuticals similar to dicoumarol, notably warfarin and some even more potent rodenticides.
Keyword: Coumarin, Warfarin, Anticoagulant activity.
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