Synthesis and Evaluation of Antimicrobial and Antioxidant Activities of Some Phenylhydrazones Derived from 4-(4'-hydrazinylphenyl)-4H-1,2,4- Triazole
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Author:
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NARAYANAN RAVISANKAR, K E POORNI
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Abstract:
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Hydrazones are the most widely used organic compounds. They are used as pigments, dyes, catalysts,
intermediates in organic synthesis and polymer stabilizers. Hydrazones have been shown to exhibit a broad
range of biological activities including antimicrobial, anti–hypertensive, anti–inflammatory, analgesics, anti–
tubercular, anti–tumour, anti–material, antioxidant, antiviral and also used as quantitative analytical reagents,
especially in colorimetric and fluorimetric determination of metal ions. The present work is based on the
above hydrazones derivative form heterocyclic substituted phenylhydrazine. The structures of the synthesized
compounds were characterized by elemental analysis and IR, 1H and 13C NMR, Mass spectral studies. All the
newly synthesized compounds were screened to antimicrobial and antioxidant activity.
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Keyword:
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Phenylhydrazones, Antimicrobial and Antioxidant.
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EOI:
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-
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DOI:
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https://doi.org/10.31838/ijpr/2021.13.02.218
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