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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Synthesis and Evaluation of Antimicrobial and Antioxidant Activities of Some Phenylhydrazones Derived from 4-(4'-hydrazinylphenyl)-4H-1,2,4- Triazole

Author: NARAYANAN RAVISANKAR, K E POORNI
Abstract: Hydrazones are the most widely used organic compounds. They are used as pigments, dyes, catalysts, intermediates in organic synthesis and polymer stabilizers. Hydrazones have been shown to exhibit a broad range of biological activities including antimicrobial, anti–hypertensive, anti–inflammatory, analgesics, anti– tubercular, anti–tumour, anti–material, antioxidant, antiviral and also used as quantitative analytical reagents, especially in colorimetric and fluorimetric determination of metal ions. The present work is based on the above hydrazones derivative form heterocyclic substituted phenylhydrazine. The structures of the synthesized compounds were characterized by elemental analysis and IR, 1H and 13C NMR, Mass spectral studies. All the newly synthesized compounds were screened to antimicrobial and antioxidant activity.
Keyword: Phenylhydrazones, Antimicrobial and Antioxidant.
DOI: https://doi.org/10.31838/ijpr/2021.13.02.218
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