IJPR  articles are Indexed in SCOPUS (2010 - 2021)Click Here     *Five Years Citation in Google scholar (2016 - 2020) is. 1451*        Now IJPR is Q2 in SJR Ranking     Scopus Coverage of IJPR (2010-2021 Issue 1)            

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
Current Issue
Article In Press
No Data found.
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
 

Article Detail

Label
Label
Validated Stability Indicating RP-HPLC Method for Valganciclovir Hydrochloride in its Pure and Pharmaceutical Dosage Form

Author: SHINDE R, M SUMITHRA
Abstract: The development and validation of a new stability indicating RP-HPLC method of Valganciclovir hydrochloride in pure and dosage forms by RP-HPLC was described as per ICH guideline. Drug was studied under isocratic condition using CHEMSIL C18 (250 X 4.6 mm), 5µm column by used a mobile phase which is isocratic containing Acetonitrile and 0.05 M ortho phosphate buffer (pH 4.0) is 60:40 v/v ratio was carried out 1.0 ml/min are be the flow rate at ambient column temperature at 254 nm. Degradation study was carried out as per ICH guidelines in all conditions. Chromatograms of various degradation studies of Valganciclovir hydrochloride reveals the no degradation was observed and suitability of the developed RP-HPLC method. Study is going on under force degradation with internal standard. Proposed method was stable and validated as per ICH guidelines and may helpful for quantification of Valganciclovir HCl in analytical laboratories. Further study was completed towards their validation and developed method was found to be precise and accurate.
Keyword: Degradation, HPLC, Method development, Validation.
DOI: https://doi.org/10.31838/ijpr/2021.13.02.207
Download: Request For Article
 




ONLINE SUBMISSION
USER LOGIN


Username
Password
Login | Register
News & Events
SCImago Journal & Country Rank

Terms and Conditions
Disclaimer
Refund Policy
Instrucations for Subscribers
Privacy Policy

Copyrights Form

0.12
2018CiteScore
 
8th percentile
Powered by  Scopus
Google Scholar

hit counters free