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Determination of Naproxen and Esomeprazole Using HPTLC
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| Author:
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VIVEK INGALE, TRUPTI JAMBHALE, VIPUL DHASADE, AMIT KASABE, SANTOSH FATTEPUR, NAGARAJA SREEHARSHA
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| Abstract:
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To simultaneously determine naproxen and esomeprazole as a bulk drug and laboratory combination, a simple,
delicate, accurate and high performance thin-layer (HPTLC) method was developed and validated. Separation
was carried out as a stationary process on aluminium-backed silica gel 60F254 HPTLC. The solvent system was
formed by mobile phase ethyl-acetate - methanol - ammonia (8.0: 1.26: 0.54 v/v). Camag TLC scanner 3 was
used in the absorbance mode at 272 nm to conduct the densitometric scanning. The method mentioned has
the benefit that it is fast and clear.
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| Keyword:
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Naproxen, Esomeprazole, HPTLC, Validation
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.02.227
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| Download:
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Request For Article
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