An Economic Evaluation of Pharmacist’ Intervention to Improve Blood Pressure Control: A Systematic Review
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Author:
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YOPI RIKMASARI, SUSI ARI KRISTINA, TRI MURTI ANDAYANI, DWI ENDARTI
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Abstract:
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Background: Suboptimal blood pressure control is a risk factor associated with cardiovascular disease. An
adequate number and dose of prescribed blood pressure medications and adherence with therapy are two
main factors that affect the patient's blood pressure control. Pharmacist intervention is expected to solve
these problems. The purpose of this review is to summarize the type of interventions involving a pharmacist to
improve blood pressure control in hypertension patients and the impact on the clinical, economic, or
humanistic outcome.
Methods: We conducted a systematic search using Pubmed, Scopus, and ScienceDirect databases published
from 2010 until 2020. The terms used in the search were hypertension and pharmacist and intervention and
cost of economic evaluation. The articles were collected according to the inclusion criteria and the quality of
the evaluation study using the 10-item Drummond Checklist then the results were extracted and analyzed
systematically.
Results: A total of four articles were carried out for analysis. The same type of intervention was found in the
physician-pharmacist collaboration and we found that the ICER value to reduce 1 mmHg of systolic in three
articles was $ 33.27, $ 22.21 and $ 36.25 per 1 mmHg SBP. For diastolic blood pressure, there were ICER
value of $ 69.98, $ 66.0 and $ 94.32 per 1 mmHg DBP and$ 53.50/1 QALY in one study.
Conclusion: It can be concluded that pharmacist intervention in the form of physician-pharmacist
collaboration is cost-effective and provides benefits to blood pressure control in hypertensive patients. Even
so, the articles discussed are still very few and pharmacoeconomics studies have not used modeling. In the
future, it is necessary to explore further about the form of doctor-pharmacist collaboration intervention in
hypertensive patients at a cost that is acceptable to interested parties and can be carried out widely in various
health services.
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Keyword:
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Hypertension, cost-effectiveness, physician-pharmacist collaboration
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EOI:
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DOI:
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https://doi.org/10.31838/ijpr/2021.13.02.184
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