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Evaluation of the use of antibiotics for UTI therapy at Primary Health Care Yogyakarta
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| Author:
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IKA PUSPITASARI, TITIK NURYASTUTI, NUNUNG YUNIARTI, YUNILISTIANINGSIH
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| Abstract:
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The use of antibiotics in primary health care, especially in the treatment of urinary tract infections (UTI), is one
that is controlled by WHO. To support WHO's antibiotic resistance control program through the GLASS
program, data on antibiotic resistance in Indonesia needs to be researched and reported as one of the national
awareness systems. This research aimed to map the microbe patterns in primary health care in Yogyakarta
City as a consideration for the guideline of empiric antibiotic therapy in urinary tract infections. Research on
antibiotic resistance patterns in UTI therapy was carried out prospectively in March to August 2019 at primary
health care (PHC) Jetis, Yogyakarta city. Patients who met the inclusion criteria were patients treated at PHC
Jetis in Yogyakarta, aged> 18 years and were given antibiotics. The culture and susceptibility of the patients'
urine specimen were examined at Microbiology Laboratory of the Faculty of Medicine, Public Health and
Nursing of UGM Yogyakarta. Meanwhile, the calculation of DDD antibiotics was carried out for the use of UTI
antibiotics from 1st January to 31st December, 2019. A total of 76.9% of UTI patients received empiric
antibiotics cotrimoxazole according to the therapy guidelines in primary health care and the national
formulary. The results of culture examination of urine specimens observed that most of them (94%) were E.
coli. Almost all tested antibiotics still showed> 80% susceptibility to E. coli, except for ampicillin. The DDD
antibiotics for UTI therapy, namely; cotrimoxazole, ciprofloxacin and ampicillin were very low, less than 4.
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| Keyword:
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antibiotic susceptibility, antibiogram, DDD, UTI, primary health care
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.02.183
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| Download:
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