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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Evaluation of the use of antibiotics for UTI therapy at Primary Health Care Yogyakarta

Author: IKA PUSPITASARI, TITIK NURYASTUTI, NUNUNG YUNIARTI, YUNILISTIANINGSIH
Abstract: The use of antibiotics in primary health care, especially in the treatment of urinary tract infections (UTI), is one that is controlled by WHO. To support WHO's antibiotic resistance control program through the GLASS program, data on antibiotic resistance in Indonesia needs to be researched and reported as one of the national awareness systems. This research aimed to map the microbe patterns in primary health care in Yogyakarta City as a consideration for the guideline of empiric antibiotic therapy in urinary tract infections. Research on antibiotic resistance patterns in UTI therapy was carried out prospectively in March to August 2019 at primary health care (PHC) Jetis, Yogyakarta city. Patients who met the inclusion criteria were patients treated at PHC Jetis in Yogyakarta, aged> 18 years and were given antibiotics. The culture and susceptibility of the patients' urine specimen were examined at Microbiology Laboratory of the Faculty of Medicine, Public Health and Nursing of UGM Yogyakarta. Meanwhile, the calculation of DDD antibiotics was carried out for the use of UTI antibiotics from 1st January to 31st December, 2019. A total of 76.9% of UTI patients received empiric antibiotics cotrimoxazole according to the therapy guidelines in primary health care and the national formulary. The results of culture examination of urine specimens observed that most of them (94%) were E. coli. Almost all tested antibiotics still showed> 80% susceptibility to E. coli, except for ampicillin. The DDD antibiotics for UTI therapy, namely; cotrimoxazole, ciprofloxacin and ampicillin were very low, less than 4.
Keyword: antibiotic susceptibility, antibiogram, DDD, UTI, primary health care
DOI: https://doi.org/10.31838/ijpr/2021.13.02.183
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