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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Evaluation of the efficacy of a dentifrice containing amine fluoride on gingival status - a clinical investigation

Author: MUNAZ MULLA, MUSHIR MULLA , RAJESH KASHYAP, SHASHIKANTH HEGDE , ARUNKUMAR MAIYA , MYTHRI SARPANGALA , FAZLUR RAHMAN SAYED
Abstract: Background: The primary objective of this study was to evaluate and compare the gingival status using the gingival index of the participants over a period of 6months. Secondary objectives were to explore between treatment differences by plaque index, simplified calculus index and modified lobene stain index at 3 months and 6 months. Methods: Plaque, gingivitis, calculus and tooth staining were assessed in 90 participants. The participants used either an amine fluoride containing toothpaste, stannous fluoride containing toothpaste or a regular dentifrice. Clinical parameters were assessed at baseline, after 3 and 6 months of toothpaste use. Statistical analysis used were CHI-square test, Students unpaired ‘t’ test, ANOVA 1-way analysis, Kruskal-Wallis test and Mann-Whitney U test. Results: After 6 months of product use, all three groups showed increase in plaque and gingival scores with no statistically significant difference. No calculus was observed in all the three groups. Stains were present more on the palatal surface than the buccal surface. Conclusions: Detrimental effects of plaque bacteria on gingival health can be prevented only by a consistently high level of motivation and adequate manual dexterity.
Keyword: plaque control; gingivitis; clinical research; amine fluoride; dentifrice; oral health
DOI: https://doi.org/10.31838/ijpr/2020.12.04.651
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