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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Effect of Central Obesity on Spread of Spinal Anesthesia

Author: DR.POOJITHA K, DR.SHAILA S.KAMATH
Abstract: Background: The difference of distribution of fat in the body can vary the level of blockade achieved by intrathecal drug, an abdominal increase may reduce the CSF volume giving a higher level of the same. This study has been conducted to know the effect of central obesity on the ascent of spinal anesthesia. Materials & Methods: Hundred patients scheduled for lower limb surgery under spinal anesthesia were allocated to either central obesity or non-central obesity group depending on their waist circumference. After induction of spinal anesthesia, maximal sensory blockade (primary outcome), time for maximal sensory block, maximum motor block, time to maximal motor block and time to bromage 0 were evaluated. Results: It was found that the sensory blockade was 2 segments higher in the CO group than the NCO group (p = 0.000). The time taken to achieve maximum sensory and motor blockade was 4 minutes and 2 minutes earlier in the CO group when compared to the NCO group, (p = 0.000) respectively and the reversion from motor blockade , that was time to bromage scale 0 was delayed by 10 minutes in the CO group in contrast to the NCO group( p = 0.001). Conclusion: Central obesity is related to more extensive spread of spinal anesthesia
Keyword: abdominal fat, drug spread, intrathecal, obesity, spinal anesthesia
DOI: https://doi.org/10.31838/ijpr/2021.13.02.141
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