Histology and Morphometric Properties of Ileum Lymphoid Tissue in Period of Neonetal Sepsis
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Author:
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KHAITOV AKBAR, RAJABBOY ISROILOV, NIZOM ERMATOV, ALLABERGANOV DILSHOD
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Abstract:
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The incidence of intestinal forms of sepsis in infants and children during the one-month period has been
increasing. The main changes in the intestinal form of sepsis are located in the small intestine, and
morphologically the appearance of erosions, wounds and necrosis leads to severe poisoning of the child's body
and the development of sepsis. Disruption of the integrity of the intestinal mucosa increases the permeability
of the hematohistiogenic barrier, local inflammatory-destructive changes in the intestine lead to circulatory
disorders, the development of ischemia and hypoxia, lysosomal hydrolases, excessive secretion of cytokines
and rapid depletion of microflora in the circulatory system. The results of our experiment showed that in the
early months of the process of adaptation of infants in the ileum to the external environment, there was an
increase in the number of reticular cells, macrophages, large blast lymphocytes, which are the main responsible
for the immune response in the lymphoid nodes.
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Keyword:
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neonetal sepsis, ileum, lymphoid tissue, morphology.
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EOI:
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-
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DOI:
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https://doi.org/10.31838/ijpr/2021.13.02.019
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