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Histopathological and Enzymatic Changes in Male Mice Liver Induced by CeO2 nanoparticle
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| Author:
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SAMAHER SABRY HAMMID, SAMI JEBER AL-MALIKI, ALI A.A.AL-ALI
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| Abstract:
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This study conducted to assess the effects cerium oxide nanoparticles on liver enzymes and hepatocellular
changes due to I/P administration of cerium oxide nanoparticles in male mice. White laboratory mice Mus
muscular L. strain BALB / C were used. The results of the current study showed a significant increase in the
level of ALT and AST enzymes for male laboratory mice injected with cerium oxide in the two doses and for
two periods compared with the control group. Microscopic examination of histological sections of the liver
showed pathological changes after injection of mice with cerium oxide in both low and high doses included
dilatation in the central vein , congestion , infiltration of inflammatory, hyperplasia of hepatic cells,
multinucleated cells and necrosis.
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| Keyword:
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Cerium oxide, liver enzymes, histopathology.
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2021.13.02.064
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| Download:
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Request For Article
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