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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Differences between Lipid Profile and Blood Pressure in Diabetes Mellitus Type 2

Author: JEKSON MARTIAR SIAHAAN, ENDY JULIANTO, HENDRIKA ANDRIANA SILITONGA
Abstract: Dyslipidemia can occur together with diabetes mellitus type 2. Diabetes or impaired glucose tolerance with hypertension was characterized by low HDL, high LDL, and high VLDL levels. The purpose of this study was to determine whether there were differences in lipid profiles with blood pressure in type 2 diabetes mellitus patients. This study was an observational analytic study with a cross-sectional approach conducted at general hospital Pirngadi Medan. The total sample was 15 patients with diabetes mellitus type 2. The research sample was taken step by step, namely purposive sampling, followed by incidental sampling. The research instrument used medical records and lipid profile data from laboratory examinations of diabetes mellitus type 2 from patients with hypertension and without hypertension. Based on the analysis using the results of a one-way correlative analytic test, it showed that there was a positive correlation between systolic blood pressure and total cholesterol levels (p = 0.267), glucose levels (p = 0.967), HDL levels (p = 0.117), LDL levels (p = 0.634) and triglyceride levels (p = 0.361) and negatively correlated with HbA1c (p = 0.370) but not significant. There was a positive correlation between diastolic blood pressure and total cholesterol levels (p = 0.114), HDL levels (p = 0.174), LDL levels (p = 0.485) and triglyceride levels (p = 0.073) and negatively correlated with HbA1C (p = 0.248), Glucose content (p = 0.699), but not significant. There was no relationship between HbA1C levels and the degree of hypertension, p = 0.600. This study concluded that there was no significant relationship between hypertensive patients and lipid profiles in people with T2DM, and there was no relationship between HbA1C levels and the degree of hypertension.
Keyword: Diabetes mellitus type 2, lipid profile, hypertension, dyslipidemia
DOI: https://doi.org/10.31838/ijpr/2021.13.02.042
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