IJPR  articles are Indexed in SCOPUS (2010 - 2021)Click Here     *Five Years Citation in Google scholar (2016 - 2020) is. 1451*        Now IJPR is Q2 in SJR Ranking     Scopus Coverage of IJPR (2010-2021 Issue 1)            

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
Current Issue
Article In Press
No Data found.
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
 

Article Detail

Label
Label
A Narrative Review: The Inflammation in Chronic Kidney Disease (CKD)

Author: DEDI RACHMADI, MOHAMMAD RUDIANSYAH, RIA BANDIARA, LEONARDO LUBIS
Abstract: The chronic kidney disease (CKD) is a serious health challenge within every community, with a rising prevalence in recent years. The contribution of the immune system and the inflammatory process is increasingly recognized as the beginning of CKD pathophysiology. Risk factors such as glomerulonephritis, lupus nephritis, diabetes mellitus, hypertension, and obstructive nephropathy also contribute to the progression of inflammation in CKD. Inflammation that occurs is triggered by both innate immunity and adaptive immunity. Inflammatory response that is related to adaptive immunity in CKD can be either cellular immunity or humoral immunity, in which they can produce pro-inflammatory mediators. Pro-inflammatory mediators can alter renal hemodynamics, sodium and water homeostasis, and blood pressure. Uncontrolled inflammation response results in glomerular, tubular, and interstitial damage. This process can cause or contribute significantly to acute kidney injury and chronic kidney disease. The consequence of CKD is end stage kidney disease (ESKD) with Malnutrition-Inflammation-Atherosclerosis (MIA) syndrome and renal anemia.
Keyword: Chronic kidney disease, inflammation, immunity, Malnutrition-Inflammation-Atherosclerosis syndrome, fibroblast
DOI: https://doi.org/10.31838/ijpr/2021.13.02.058
Download: Request For Article
 




ONLINE SUBMISSION
USER LOGIN


Username
Password
Login | Register
News & Events
SCImago Journal & Country Rank

Terms and Conditions
Disclaimer
Refund Policy
Instrucations for Subscribers
Privacy Policy

Copyrights Form

0.12
2018CiteScore
 
8th percentile
Powered by  Scopus
Google Scholar

hit counters free