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Flow Propagation velocity as a marker of impaired early diastolic flow in Pre-hypertensive individuals
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| Author:
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AMINA A.B.AL-DEJELI, HAMID MOHAMMED HUSSEIN ABBAS, BATOOL SAHIB JBARAH, ASAAD HASAN NOAMAN AL-ABOODI
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| Abstract:
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The major problem in patients with hypertension is the cardiac complication as subclinical insults can occur in those patients affecting both the function as well as the structure of the left ventricle. Diastolic heart failure with preserved ejection fraction is commonly occur in hypertensive patients, thus early detection of changes in diastolic parameters before reaching hypertensive level is of important value. We targeted to define whether flow propagation velocity in pre-hypertensive subjects (BP 120-139/ 80-89 mmHg) have early alterations compared to individuals with optimal BP (BP 100-119/ 60-79 mmHg). Methods: A total of 100 individuals participating in this study, 50 adults, aged 38.5±2.9 years, 62% male as a pre-hypertensive group (SBP: 123.4±2.6 , DBP: 85.6±1.57 mmHg) and 50 adults, aged 38.14±3.4, 60% male, as a control, (SBP: 115.15±4.6, DBP: 64.85±2.25 mmHg). Clinical & echocardiographic examinations were performed in all individuals. The classification as normal and prehypertension was based on the European guidelines for the classification of office blood pressure level. Echocardiographic assessment of diastolic function was performed by measuring flow propagation. Results: There was a decrease in the flow propagation velocity in pre-hypertensive individuals in comparison to control (36.95±1.4 vs. 53.4±1.3cm/s,P < 0.001 respectively).Conclusion: In this study, pre-hypertensive individuals showed lower flow propagation velocity in comparison to individuals with optimal blood pressure suggesting early subclinical diastolic insults.
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| Keyword:
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Pre-hypertension, diastolic dysfunction, flow propagation velocity
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.03.511
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